The Hepatobiliary Research Group, led by Dr. Christian Stöß, in the Department of Surgery, is dedicated to advancing the understanding of liver biology in health and disease. We investigate the cellular and molecular mechanisms underlying the spectrum of metabolic liver disease, liver regeneration, fibrosis, inflammation, and liver cancer, with a strong focus on translating fundamental discoveries into improved medical therapies. By integrating comprehensive clinical data, patient-derived samples, preclinical models, advanced imaging, and precision tissue models, we explore how immune cells, regulated cell death pathways, and the hepatic microenvironment shape disease progression, tissue repair, regeneration, and postoperative recovery. Our ultimate goal is to identify novel therapeutic targets and develop innovative treatment strategies to improve outcomes for patients with hepatobiliary diseases and those undergoing liver surgery.